:root {
    --gaps: 0.5em;
}

body {
    margin: 0;
    box-sizing: content-box;
    display: flex;
    flex-direction: column;
    font-size: 14pt;
    font-family: Arial, Helvetica, sans-serif;
}
#wrapper {
    width: 100%;
    height: 100vh;
    padding: 2.5% 5%;
    box-sizing: border-box;
    display: flex;
    flex-direction: row;
    gap: calc(2 * var(--gaps));
}

#calculate-wrapper {
    display: flex;
    flex-direction: column;
    align-items: center;
}
#calculate {
    height: 2.5em;
    font-size: 14pt;
    width: 80%;
}
textarea {
    font-size: 14pt;
}
#in-seq {
    resize: vertical;
    min-height: 6em;
    font-size: 12pt;
} 
div {
    flex-direction: row;
}
.header {
    width: 100%;
    height: 10vh;
    display: flex;
    align-items: center;
}
.rev-comp-link {
    display: none;
}
input#in-cds-radio:checked ~ .rev-comp-link {
    display: inline;
}
.body-left {
    inline-size: 0;
    flex: 1 0 0;
    display: flex;
    flex-direction: column;
    gap: var(--gaps);
}
.body-right {
    inline-size: 0;
    flex: 0 0 22%;
    display: flex;
    flex-direction: column;
    gap: var(--gaps);
    overflow: hidden;
}
.mode-select {
    display: flex;
    justify-content: center;
    line-height: 1.2;
    gap: 0.2em;
}
.mode-select label {
    border-radius: 0.2em;
    padding: 0.1em;
}
.insert {
    display: none;
}
.remove {
    display: none;
}
#wrapper:has(#mode-insert:checked) .insert {
    display: initial;
}
#wrapper:has(#mode-remove:checked) .remove {
    display: initial;
}
button.insert {
    background-color: #cec;
    border-color: #7c7;
}
button.insert:hover {
    background-color: #ada;
    border-color: #5a5;
}
button.insert:active {
    background-color: #d8f8d8;
}
button.remove {
    background-color: #fbb;
    border-color: #d88;
}
button.remove:hover {
    background-color: #eaa;
    border-color: #b66;
}
button.remove:active {
    background-color: #fdd;
}
#custom-seq {
    resize: vertical;
    box-sizing: border-box;
    width: 100%;
    min-height: 5.5ex;
}
.re-box {
    display: flex;
    flex-direction: column;
    gap: 0.1em;
}
select[name=re-set] {
    width: 100%;
    font-size: 12pt;
}
select[name=re-set] option {
    padding: 0.1em 0.4em;
}
span.highlight {
    border-radius: 0.2em;
}
span.highlight-insert {
    background-color: lightgreen;
}
span.highlight-remove-outer {
    /* background-color: #ffd8d8; */
    outline: 1px solid #ffaaaa;
}
span.highlight-remove {
    background-color: #ffaaaa;
}
table#results {
    display: block;
    overflow: scroll;
    flex: 1 0 0;
    font-family: monospace;
    font-size: 12pt;
    white-space: pre;
    width: 100%;
    border-collapse: collapse;
}
table#results > tr:first-child {
    background-color: white;
}
table#results > tr:first-child > th:first-child {
    background-color: white;
    z-index: 4;
    left: 0;
}
table#results > tr:first-child > th {
    padding-bottom: 0.2em;
}
#results th {
    top: 0;
    position: sticky;
    background-color: white;
    z-index: 3;
}
tr > td:first-child {
    left: 0;
    position: sticky;
    background-color: white;
    z-index: 2;
    white-space: nowrap;
}
tr > td:first-child, tr > th:first-child {
    padding-left: 0.5em;
    padding-right: 0.5em;
}
tr:not(:first-child) {
    box-sizing: border-box;
    border-top: 1px solid rgba(0,0,0,0.15);
    border-bottom: 1px solid rgba(0,0,0,0.15);
}
#results tr > td:first-child {
    font-weight: bold;
}
.status-string {
    padding-left: 0.5em;
    position: sticky;
    left: 0;
    font-weight: bold;
}
.re-list-wrapper {
    display: flex;
    flex-direction: column;
    height: 0;
    flex: 1;
}
.re-list-wrapper input[type=text] {
    width: 0;
    font-size: 100%;
}
#restriction-enzymes td {
    padding-left: 0;
}
th {
    text-align: left;
}
th#table-topleft {
    font-family: Arial;
    font-weight: normal;
    font-size: 10pt;
    text-align: center;
    vertical-align: bottom;
    padding-right: 0.2em
}
label {
    padding-left: 0.2em;
}
.noselect {
    user-select: none;
}
table, textarea, select, button, input[type=text], input[type=number] {
    border: 1px solid lightgray;
    border-radius: 5px;
}
input[type=text], input[type=number] {
    border-radius: 2.5px;
}
input[type=number] {
    font-size: 100%;
    width: 4ch;
}
select:focus, textarea:focus, input[type=text]:focus, input[type=number]:focus {
    outline: none;
    border-color: gray;
}
textarea {
    padding: 0 0.25em;
}
button {
    background-color: #eee;
    user-select: none;
}
button:hover {
    border-color: gray;
    background-color: #ddd;
}
button:active {
    background-color: #eee;
}
select {
    font-family: inherit;
    font-size: 100%;
}
.action-link {
    color: dodgerblue;
    text-decoration: 1px dashed underline;
    cursor: pointer;
    user-select: none;
}
.action-link:hover {
    color: royalblue;
}
#crosshair {
    display: none;
    position: absolute;
    top: 100px;
    left: 100px;
    height: 500px;
    font-family: monospace;
    font-size: 12pt;
    width: 1ch;
    background-color: rgba(0,0,0,0.04);
    z-index: 999;
    pointer-events: none;
    border-left: 1px solid rgba(0,0,0,0.15);
    border-right: 1px solid rgba(0,0,0,0.15);
}